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Member and Recipient Service Line: 1-877-685-2415
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Fecal Microbiota Transplantation
Clostridium difficile is a disease-causing bacterium that can infect the large bowel and cause colitis.
Fecal microbiota transplantation (FMT) is the introduction of saline-diluted fecal matter (e.g., fecal suspension) derived from a healthy human donor into the gastrointestinal (GI) tract of an individual diagnosed with recurrent clostridium difficile infection (CDI), who has failed multiple attempts at conventional antibiotic therapy.
Clostridium difficile recurrence is defined by complete abatement of CDI symptoms while on appropriate therapy, followed by subsequent reappearance of diarrhea and other symptoms after treatment has been stopped. Recurrence must be distinguished from persistent diarrhea without resolution during initial therapy, which prompts an evaluation for other causes.
Recurrent clostridium difficile is associated with a decrease in fecal microbial diversity deficient in bacteroides and firmicutes, both of which generally dominate within the gut. Transplantation of stool from a healthy human donor to an individual with recurrent clostridium difficile restores the microbial deficiency and breaks the cycle of recurrence.
Fecal microbiota transplantation involves the restoration of the colonic flora by introducing healthy bacterial flora through infusion of stool by either retention enema, nasogastric tube, nasoduodenal tube, nasojejunal tube, colonoscope, an upper tract endoscope, or a combination of upper and lower approaches obtained from a healthy human donor.
Commonly, gastroenterologists recommend that fecal donors be healthy family members (i.e., parents, siblings, adult children of older beneficiaries) or spouses or significant partners who have common genetic and environmental factors.
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
Exclusions
Medicaid shall not cover Fecal Microbiota Transplantation in the following situations:
- a. when a beneficiary is under 21 years of age;
- b. when an attempt to treat the recurrent CDI with antibiotic(s) was not tried
and was not successful, before performing fecal microbiota transplantation;
- c. for inflammatory bowel disease;
- d. for ulcerative colitis;
- e. for Crohn’s disease;
- f. for irritable bowel disease; or
- g. for refractory constipation.
Note: In the absence of an alternative diagnosis, the beneficiary shall be considered to have a refractory illness.
Place of Service
Clinic, Outpatient hospital, Inpatient hospital
How to Submit
Please submit your request to Trillium Health Resources
Resources
G0463 25 HOSPITAL OUTPATIENT CLINIC VISIT FOR ASSESSMEN
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
How to Submit
N/A - No authorization is required
Collection of venous blood by venipuncture or urine sample by catheterization from an individual in a skilled nursing facility (SNF) or by a laboratory on behalf of a home health agency (HHA)
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
How to Submit
N/A - No authorization is required
Hepatitis C antibody screening for individual at high risk and other covered indication(s)
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
How to Submit
N/A - No authorization is required
HIV antigen/antibody, combination assay, screening
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
How to Submit
N/A - No authorization is required
Infectious agent detection by nucleic acid (DNA or RNA); human papillomavirus HPV), high-risk types (e.g., 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68) for cervical cancer screening, must be performed in addition to pap test
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
How to Submit
N/A - No authorization is required
G0477 DRUG TEST(S), PRESUMPTIVE,ANY NUMBER OF DRUG CLASSES;ANY NUMBER OF DEVICES OR PROCEDURES,(E.G.,IMMUNOASSAY) CAPABLE OF BEING READ BY DIRECT OPTICAL OBSERVATION ONLY (E.G.,DIPSTICKS,CUPS,CARDS,CARTRIDGES),INCLUDES SAMPLE VALIDATION WHEN PERFORME
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
How to Submit
N/A - No authorization is required
G0478 Drug test(s), presumptive, any number of drug classes; any number of devices or procedures, (e.g., immunoassay) read by instrument-assisted direct optical observation (e.g., dipsticks, cups, cards, cartridges), includes sample validation when p
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
How to Submit
N/A - No authorization is required
G0479 59 DRUG TEST(S),PRESUMPTIVE,ANY NUMBER OF DRUG CLASSES;ANY NUMBER OF DEVICES OR PROCEDURES BY INSTRUMENTED CHEMISTRY ANALYZERS UTILIZING IMMUNOASSAY,ENZYME ASSAY,TOF,MALDI,LDTD,DESI,DART,GHPC,GC MASWS SPECTROMETRY),
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
How to Submit
N/A - No authorization is required
G0480 59 Drug test(s), definitive, utilizing drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to, GC/MS (any type, single or tande
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
How to Submit
N/A - No authorization is required
G0481 DRUG TEST(S), DEFINITIVE, UTILIZING DRUG IDENTIFICATION METHODS ABLE TO IDENTIFY INDIVIDUAL DRUGS AND DISTINGUISH BETWEEN STRUCTURAL ISOMERS;
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
How to Submit
Please submit your request to Trillium Health Resources
G0482 DRUG TEST DEF 15-21 CLASSES
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
How to Submit
Please submit your request to Trillium Health Resources
G0483-DRUG TEST DEF 22+ CLASSES
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
How to Submit
Please submit your request to Trillium Health Resources
Dialysis procedure at a Medicare certified ESRD facility for acute kidney injury without ESRD
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
How to Submit
N/A - No authorization is required
Skilled services of a registered nurse (RN) for the observation and assessment of the patient's condition, each 15 minutes (the change in the patient's condition requires skilled nursing personnel to identify and evaluate the patient's need for possible m
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
Reauthorization Guidelines
See the Carolina Complete Health site for specific requirements
How to Submit
Please submit your request to Carolina Complete Health through Availity
Skilled services of a licensed practical nurse (LPN) for the observation and assessment of the patient's condition, each 15 minutes (the change in the patient's condition requires skilled nursing personnel to identify and evaluate the patient's need for p
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
Reauthorization Guidelines
See the Carolina Complete Health site for specific requirements
How to Submit
Please submit your request to Carolina Complete Health through Availity
Skilled services of a registered nurse (RN), in the training and/or education of a patient or family member, in the home health or hospice setting, each 15 minutes
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
Reauthorization Guidelines
See the Carolina Complete Health site for specific requirements
How to Submit
Please submit your request to Carolina Complete Health through Availity
Skilled services of a licensed practical nurse (LPN), in the training and/or education of a patient or family member, in the home health or hospice setting, each 15 minutes
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
Reauthorization Guidelines
See the Carolina Complete Health site for specific requirements
How to Submit
Please submit your request to Carolina Complete Health through Availity
Hepatitis B screening in nonpregnant, high-risk individual includes hepatitis B surface antigen (HBSAG), antibodies to HBSAG (anti-HBS) and antibodies to hepatitis B core antigen (anti-HBC), and is followed by a neutralizing confirmatory test, when perfor
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
How to Submit
N/A - No authorization is required
Rural health clinic or federally qualified health center (RHC/FQHC) only, psychiatric collaborative care model (psychiatric COCM), 60 minutes or more of clinical staff time for psychiatric COCM services directed by an RHC or FQHC practitioner (physician,
Authorization Guidelines
Please submit any records and any other information that you believe support the member has met the applicable medical necessity criteria to Trillium.
How to Submit
N/A - No authorization is required
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